Ashkenazi E, Constantini S, Shoshan Y, Umansky F, Shalit M
Dept. of Neurosurgery, Hadassah, University Hospital, Jerusalem.
Harefuah. 1990 Dec 2;119(11):359-61.
We present a series of 20 patients (11 males) operated on for craniopharyngioma through a frontal craniotomy during an 11-year period. They ranged in age from 7 months to 58 years (mean 20 years). The most common symptoms were headaches, blurred vision and endocrine disorders. The perioperative mortality was 5% and morbidity 25%. 5 (25%) patients need reoperation; 13 (65%) received additional radiation therapy. In 94% visual function improved. 65% continued to have or developed endocrine problems, although all were well controlled with supplemental therapy. These results, similar to those reported from other centers, justify a combination of radical surgery and radiation therapy for this condition.
我们报告了一组20例经额开颅手术治疗颅咽管瘤的患者(11例男性),手术时间跨度为11年。患者年龄从7个月至58岁不等(平均20岁)。最常见的症状是头痛、视力模糊和内分泌紊乱。围手术期死亡率为5%,发病率为25%。5例(25%)患者需要再次手术;13例(65%)接受了额外的放射治疗。94%的患者视觉功能得到改善。65%的患者持续存在或出现内分泌问题,尽管所有问题均通过补充治疗得到良好控制。这些结果与其他中心报告的结果相似,证明了针对这种疾病采用根治性手术和放射治疗相结合的方法是合理的。