乳腺癌患者经外周静脉穿刺中心静脉置管相关上肢深静脉血栓形成的诊断、预防及治疗
Diagnosis prevention and treatment for PICC-related upper extremity deep vein thrombosis in breast cancer patients.
作者信息
Xing Lei, Adhikari Vishnu Prasad, Liu Hong, Kong Ling Quan, Liu Sheng Chun, Li Hong Yuan, Ren Guo Sheng, Luo Feng, Wu Kai Nan
机构信息
Department of General Surgery, First Affiliated Hospital, Chongqing Medical University, Chongqing, China.
出版信息
Asia Pac J Clin Oncol. 2012 Sep;8(3):e12-6. doi: 10.1111/j.1743-7563.2011.01508.x. Epub 2012 Mar 12.
AIM
To study the incidence, diagnosis, prevention and treatment of peripherally inserted central catheter (PICC)-related upper extremity deep vein thrombosis (DVT) in breast cancer patients using a PICC catheter for chemotherapy.
METHODS
The data of the incidence, diagnosis and treatment of PICC-related upper extremity DVT in 187 breast cancer patients using a PICC catheter for chemotherapy, from August 2009 to July 2011 were retrospectively analyzed.
RESULTS
In total 188 PICC were inserted between August 2009 and July 2011 and followed up for a total of 14 399 catheter-days (median placement, 76.6 days; range, 1 to 170 days). Four (2.1%) of 188 PICC were removed as a result of PICC-related upper extremity DVT in 14 to 112 catheter-days, at a rate of 0.28/1000 catheter-days.
CONCLUSION
The use of PICCs in breast cancer patients for chemotherapy is safe and effective. However, some patients may develop catheter-related upper extremity DVT. In order to minimize complications, we should pay attention to its early symptoms and signs, as well as the timely removal of the catheter and appropriate anti-coagulant treatment.
目的
研究采用经外周静脉穿刺中心静脉置管（PICC）进行化疗的乳腺癌患者中，PICC相关上肢深静脉血栓形成（DVT）的发生率、诊断、预防及治疗情况。
方法
回顾性分析2009年8月至2011年7月期间187例采用PICC进行化疗的乳腺癌患者中PICC相关上肢DVT的发生率、诊断及治疗数据。
结果
2009年8月至2011年7月期间共置入188根PICC，总随访导管日数为14399日（中位置管时间76.6日；范围1至170日）。188根PICC中有4根（2.1%）因PICC相关上肢DVT在置管14至112日时被拔除，发生率为0.28/1000导管日。
结论
乳腺癌患者使用PICC进行化疗安全有效。然而，部分患者可能发生导管相关上肢DVT。为使并发症降至最低，应注意其早期症状和体征，以及及时拔除导管并进行适当的抗凝治疗。
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