Ospedale Regionale Generale F. Miulli Strada Prov., 127 Acquaviva - Santeramo Km. 4,100, 70021 Acquaviva delle Fonti (BA), Italy.
Int J Oral Maxillofac Surg. 2013 Mar;42(3):380-5. doi: 10.1016/j.ijom.2012.07.013. Epub 2012 Aug 13.
Diffuse-type giant cell tumour (DTGCT) is a benign but destructive proliferative disorder of the synovium of joint capsules, tendons and bursae. Lesions originating from the articular synovium may grow intra-articularly or expand widely extra-articularly. Rare cases may develop only in peri-articular tissues. Temporomandibular joint (TMJ) involvement is exceptional and only two cases of purely extra-articular TMJ-DTGCT have been reported. The authors report an additional case of extra-articular TMJ-DTGCT. The clinical features, histopathological characteristics, imaging modalities and diagnostic methods for DTGCT are discussed together with a literature review based on the clinical aspects of TMJ involvement.
弥漫型巨细胞瘤（DTGCT）是一种良性但具有破坏性的滑膜增生性疾病，可累及关节囊、肌腱和滑囊。起源于关节滑膜的病变可在关节内生长或广泛扩展至关节外。罕见情况下，病变仅发生于关节周围组织。颞下颌关节（TMJ）受累非常罕见，仅有两例纯粹的关节外 TMJ-DTGCT 被报道。作者报告了一例额外的关节外 TMJ-DTGCT 病例。本文讨论了 DTGCT 的临床特征、组织病理学特征、影像学方式和诊断方法，并基于 TMJ 受累的临床方面进行了文献复习。
