Institut für Pharmazeutische Chemie, Philipps-Universität Marburg, Marbacher Weg 6, D-35032 Marburg, Germany.
Int J Med Microbiol. 2012 Oct;302(4-5):165-71. doi: 10.1016/j.ijmm.2012.07.009. Epub 2012 Aug 13.
There are quite a number of antimalarial compounds in different states of preclinical and clinical development. Among those in advanced stages, combinations of known drugs or new substances from drug classes already used in antimalarial therapy are predominant. More compounds with novel or even unknown mechanism of action are found among those compounds which are in less advanced stages of development.
有相当数量的抗疟化合物处于临床前和临床开发的不同阶段。在那些处于先进阶段的化合物中，已知药物的组合或已经用于抗疟治疗的药物类别中的新物质占主导地位。在开发程度较低的化合物中，发现了更多具有新颖甚至未知作用机制的化合物。
