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腰椎矿物质测定法与髂嵴组织形态计量学:同一受试者多个参数比较的初步结果

Mineralometry of the lumbar spine and histomorphometry of the iliac crest: preliminary results of a comparison of several parameters in the same individual.

作者信息

Portigliatti Barbos M, Cadario A, Canavese C, Isaia G C, Salamano G, Viglino C

机构信息

Dipartimento di Traumatologia, Ortopedia e Medicina del Lavoro, Torino.

出版信息

Ital J Orthop Traumatol. 1990 Jun;16(2):241-6.

PMID:2289886
Abstract

Twelve patients affected with various bone pathologies (osteoporosis, renal osteodystrophy, osteogenesis imperfecta, hyperparathyroidism) were submitted to mineralometry of the lumbar spine with double photonic ray and transiliac biopsy for histomorphometry. A comparison of the values obtained for the mineralometric and histomorphometric parameters--despite the small number of cases--revealed a correlation between bone mineral content of the lumbar spine and trabecular and cortical bone volume of the iliac crest. The correlation is even more significant for the sum of these last two parameters. It may be concluded that: 1) both the methods have predictive values for an evaluation of osteopenia; 2) the measurement of cortical and subcortical bone volume increases the significance of the histomorphometric finding (which is usually limited to the trabecular bone volume); 3) there is a correlation between histomorphometry (iliac crest bone volume) and mineralometry (lumbar spine with double photonic ray) in the same individual.

摘要

12名患有各种骨病(骨质疏松症、肾性骨营养不良、成骨不全、甲状旁腺功能亢进)的患者接受了腰椎双光子射线骨密度测定和髂骨活检以进行组织形态计量学分析。尽管病例数量较少,但对骨密度测定和组织形态计量学参数所得值进行比较后发现,腰椎骨矿物质含量与髂嵴小梁骨和皮质骨体积之间存在相关性。对于后两个参数的总和,这种相关性更为显著。可以得出以下结论:1)两种方法对于评估骨质减少均具有预测价值;2)皮质骨和皮质下骨体积的测量增加了组织形态计量学结果的意义(该结果通常仅限于小梁骨体积);3)在同一个体中,组织形态计量学(髂嵴骨体积)与骨密度测定(腰椎双光子射线)之间存在相关性。

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