Department of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, Peking University, Beijing, China.
Oral Surg Oral Med Oral Pathol Oral Radiol. 2013 Dec;116(6):e478-84. doi: 10.1016/j.oooo.2012.02.036. Epub 2012 Aug 15.
The objective of this study was to analyze the clinical and laboratory features, treatments, and prognosis of ankylosing spondylitis (AS) associated with bilateral temporomandibular joint ankylosis (TMJA).
A PubMed search was conducted from 1966 to date, and the references of published studies were also checked to identify additional cases. Information from these reports and our report were compared and analyzed.
Published literature in the past 36 years, which included 8 cases, were reviewed. The mean (SD) age at diagnosis of AS and bilateral TMJA was 21.00 (6.35) and 32.50 (13.43) years, respectively. Ankylosis of cervical vertebra was described in all patients. Total alloplastic joints and artificial condyle replacements were also reported in recent years. The slices of ankylotic mass showed the marrow was infiltrated by eosinophilic granulocytes.
Evaluating temporomandibular joint (TMJ) function is strongly recommended in patients who have a long history of AS, particularly in cases involving cervical vertebrae disease.
本研究旨在分析伴有双侧颞下颌关节（TMJ）强直的强直性脊柱炎（AS）的临床和实验室特征、治疗方法和预后。
从 1966 年至今进行了 PubMed 检索，并查阅了已发表研究的参考文献，以确定其他病例。对这些报告和我们报告中的信息进行了比较和分析。
回顾了过去 36 年发表的文献，其中包括 8 例患者。AS 和双侧 TMJA 的平均（SD）发病年龄分别为 21.00（6.35）岁和 32.50（13.43）岁。所有患者均有颈椎强直。近年来也有报道全关节假体和人工髁置换术。强直肿块的切片显示骨髓被嗜酸性粒细胞浸润。
对于有 AS 病史较长的患者，特别是伴有颈椎疾病的患者，强烈建议评估 TMJ 功能。
