Cesagen, Cardiff University, Cardiff, Wales, UK.
Best Pract Res Clin Obstet Gynaecol. 2012 Oct;26(5):541-50. doi: 10.1016/j.bpobgyn.2012.06.003. Epub 2012 Aug 14.
The ethics of diagnosis and management of fetal genetic disorders are particularly controversial because of the contested status of the fetus and perceptions of genetics. An additional complicating factor is the potential conflict between mother and fetus. Ethical issues in diagnosis include the nature and purpose of the diagnosis itself, and management of the information. Management of the disorder includes issues of termination as an option, and the emerging field of fetal gene therapy with associated issues of somatic versus germ-line interventions.
胎儿遗传疾病的诊断和处理的伦理问题尤其具有争议性，因为胎儿的地位和遗传学的认知都存在争议。一个额外的复杂因素是母亲和胎儿之间潜在的冲突。诊断中的伦理问题包括诊断本身的性质和目的，以及对信息的处理。疾病的处理包括终止妊娠作为一种选择的问题，以及新兴的胎儿基因治疗领域，涉及体细胞与种系干预的相关问题。
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