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医学生遗传学教学中的伦理挑战。

Ethical challenges in teaching genetics for medical students.

作者信息

Nagle Erika, Kažoka Dzintra

机构信息

Department of Biology and Microbiology, Riga Stradinš University, Riga, Latvia.

Institute of Anatomy and Anthropology, Department of Morphology, Riga Stradinš University, Riga, Latvia.

出版信息

J Microbiol Biol Educ. 2014 Dec 15;15(2):181-5. doi: 10.1128/jmbe.v15i2.776. eCollection 2014 Dec.

Abstract

Although inclusion of ethics as a study course in medical students' curricula is a common practice, special approaches in teaching ethics in the context of genetics should be considered. In the realm of genomics, there are several ethically sensitive topics such as diagnosis of genetic diseases, in vitro fertilization, and identification of genetic susceptibility to common diseases. In addition, in communication with the general public, genetic terms should be used with caution. Demonstration of the phenotypes of affected individuals should be regarded as a particular aspect of teaching genetics. In a description of a patient's phenotype, not only is it necessary to provide scientifically precise characteristics of a patient; voice timbre, facial expression, and body language should also be carefully controlled. Furthermore, in medicine, the theory-practice gap is a problematic aspect, and students often find it difficult to apply knowledge on ethical issues to real situations in clinics. For this purpose, clinical cases are presented during classes and their analysis requires a very respectful attitude on the part of both students and lecturers. For many genetic diseases, evaluation of minor anomalies such as a curved fifth finger, low situated ears, or missing of some teeth is required. Some minor anomalies are found in healthy individuals too, and interpretation of such features must therefore be considered carefully. This article describes our experiences in teaching genetics at Riga Stradinš University, ethical problems faced while teaching genetics, and their solutions.

摘要

虽然将伦理学作为医学生课程中的一门学习课程是常见做法,但应考虑在遗传学背景下教授伦理学的特殊方法。在基因组学领域,存在几个伦理上敏感的话题,如遗传疾病的诊断、体外受精以及常见疾病遗传易感性的鉴定。此外,在与公众沟通时,应谨慎使用遗传学术语。展示受影响个体的表型应被视为遗传学教学的一个特殊方面。在描述患者的表型时,不仅要提供患者科学精确的特征;嗓音音色、面部表情和肢体语言也应仔细控制。此外,在医学中,理论与实践的差距是一个有问题的方面,学生们常常发现难以将伦理问题的知识应用于临床实际情况。为此,课堂上会呈现临床病例,其分析要求学生和讲师都持非常尊重的态度。对于许多遗传疾病,需要评估一些轻微异常,如弯曲的第五指、低位耳或某些牙齿缺失。一些轻微异常也会在健康个体中出现,因此必须仔细考虑对这些特征的解读。本文描述了我们在里加斯特拉迪纳斯大学教授遗传学的经验、教授遗传学过程中面临的伦理问题及其解决方案。

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