Vancouver General Hospital, 2775 Laurel St, Vancouver, British Columbia, Canada.
Can J Cardiol. 2013 Apr;29(4):519.e1-3. doi: 10.1016/j.cjca.2012.06.010. Epub 2012 Aug 15.
Fibromuscular dysplasia (FMD) is increasingly recognized as a nonatherosclerotic pathology in young women presenting with acute coronary syndromes. The angiographic appearance of these lesions may mimic typical atherosclerosis, and a high index of suspicion is needed. The pathophysiological changes in the intima and media alter the vessel's elasticity and may adversely affect the lesion's response to balloon dilatation and stenting. Intracoronary imaging is therefore useful when planning percutaneous intervention. We present a case of stent implantation in a coronary FMD lesion complicated by perforation with intravascular ultrasound images demonstrating the typical changes of FMD.
纤维肌性发育不良（FMD）在表现为急性冠状动脉综合征的年轻女性中越来越被认为是非动脉粥样硬化性病变。这些病变的血管造影表现可能类似于典型的动脉粥样硬化，因此需要高度怀疑。内皮层和中膜的病理生理变化改变了血管的弹性，并可能对病变对球囊扩张和支架置入的反应产生不利影响。因此，在计划经皮介入治疗时，冠状动脉成像很有用。我们介绍了一例 FMD 病变支架植入术后并发穿孔的病例，血管内超声图像显示了 FMD 的典型改变。
