[胆管梗阻和胆管炎对血清SPan-1水平的影响]

[Effect of biliary obstruction and cholangitis on serum SPan-1 level].

作者信息

Matsumoto S, Muranaka T, Hanada K, Matsuura Y, Oshiumi Y

机构信息

Department of Radiology, National Fukuoka Central Hospital.

出版信息

Kaku Igaku. 1990 Dec;27(12):1443-6.

PMID:2290216

Abstract

We investigated the effect of biliary obstruction and cholangitis on serum SPan-1 level in 14 patients (5 patients with pancreatic cancer and 9 patients with biliary tract cancer) who were performed PTCD for biliary obstruction. 1 out of 5 cases with pancreatic cancer and 8 out of 9 cases with biliary tract cancer showed a decrease of SPan-1 level with improvement of jaundice. It suggested that the effect of biliary obstruction and cholangitis on serum SPan-1 level was much more in biliary tract cancer than in pancreatic cancer. There was no significant difference in changes of between serum SPan-1 level and serum CA 19-9 level after PTCD. We conclude that the effect of biliary obstruction and cholangitis on serum SPan-1 level is almost same on serum CA 19-9 level.

摘要

我们对14例因胆道梗阻接受经皮肝穿刺胆道引流术（PTCD）的患者（5例胰腺癌患者和9例胆管癌患者），研究了胆道梗阻和胆管炎对血清SPan-1水平的影响。5例胰腺癌患者中有1例，9例胆管癌患者中有8例血清SPan-1水平随黄疸改善而下降。这表明胆道梗阻和胆管炎对血清SPan-1水平的影响在胆管癌中比在胰腺癌中更为明显。PTCD术后血清SPan-1水平与血清CA 19-9水平的变化无显著差异。我们得出结论，胆道梗阻和胆管炎对血清SPan-1水平的影响与对血清CA 19-9水平的影响几乎相同。