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[实验室及仪器检查方法参数在急性心肌缺血性病变诊断中的相关性]

[Correlations of laboratory and instrumental method parameters in the diagnosis of acute ischemic lesion of the myocardium].

作者信息

Makarovskiĭ V V

出版信息

Kardiologiia. 1990 Oct;30(10):35-9.

PMID:2290268
Abstract

The detection rate was examined for ECG (EchoECG) equivalents of clinical coronary heart disease (CHD) forms, such as angina pectoris, focal myocardial dystrophy, small and large myocardial infarction, at various levels of the peak activity of blood creatine phosphokinase in the acute period of the disease. A series of investigations revealed in the acute period the time when myoglobin, CPK, CPK MB, AST, and LDH attained their maximal blood content, which were directly related to the molecular weight of proteins. The findings allowed the author to consider a relationship between the values obtained by diagnostic techniques and the time course of an infarct process, the mass of ischemic necrosis and its topography in the myocardium.

摘要

在疾病急性期血肌酸磷酸激酶峰值活性的不同水平下,对临床冠心病(CHD)类型(如心绞痛、局灶性心肌营养不良、大小心肌梗死)的心电图(EchoECG)等效物的检出率进行了检查。一系列研究揭示了在急性期肌红蛋白、CPK、CPK MB、AST和LDH达到其最大血液含量的时间,这些时间与蛋白质的分子量直接相关。这些发现使作者能够考虑诊断技术所获得的值与梗死过程的时间进程、缺血性坏死的范围及其在心肌中的位置之间的关系。

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