Golev G D
Klin Med (Mosk). 1990 Sep;68(9):92-5.
The course of the acute renal failure (ARF) was studied in 3 patients with rhabdomyolysis (1 with the position compression syndrome, 1 with march myoglobinuria, and 1 with chronic recurrent rhabdomyolysis). The ARF syndromes were revealed in 2 patients 5-7 days after onset of the disease; in 1 patient (chronic recurrent rhabdomyolysis), ARF recurred. This suggests that the patients developed acute interstitial nephritis (AIN) Prolonged myolytic conditions due to ill-timed initiation of treatment led to the fact that AIN was complicated by ARF in 2 patients, and 1 patient with chronic myopathy had an "immune readiness" for myoglobin to affect the kidneys, which also resulted in ARF. It was stressed that the methods of extracorporeal detoxification (hemodialysis, hemosorption) were highly effective in treating AIN and ARF.
对3例横纹肌溶解症患者（1例患有体位压迫综合征，1例患有行军性肌红蛋白尿，1例患有慢性复发性横纹肌溶解症）的急性肾衰竭病程进行了研究。2例患者在疾病发作后5 - 7天出现急性肾衰竭综合征；1例患者（慢性复发性横纹肌溶解症）出现急性肾衰竭复发。这表明患者发生了急性间质性肾炎（AIN）。由于治疗启动不及时导致肌溶解状态持续时间延长，使得2例患者的AIN并发急性肾衰竭，1例患有慢性肌病的患者对肌红蛋白影响肾脏具有“免疫易感性”，这也导致了急性肾衰竭。强调了体外解毒方法（血液透析、血液吸附）在治疗AIN和急性肾衰竭方面非常有效。
