Department of Psychology, University of Minnesota, USA.
J Abnorm Psychol. 2013 Feb;122(1):86-92. doi: 10.1037/a0029598. Epub 2012 Aug 20.
Multivariate comorbidity research indicates mood and anxiety (internalizing) disorders share one or more common liabilities, but categorical, dimensional, and hybrid accounts of these liabilities have not been directly compared. We modeled seven internalizing disorders in a nationally representative sample of 43,093 individuals via confirmatory factor, latent class, exploratory factor mixture, and exploratory structural equation modeling analyses. A two-dimensional (distress-fear) liability structure fit best and replicated across gender, assessment waves, and lifetime/12-month diagnoses. These liabilities, not disorder-specific variation, predicted future internalizing pathology, suicide attempts, angina, and ulcer.
多变量共病研究表明，情绪和焦虑（内在）障碍具有一个或多个共同的缺陷，但这些缺陷的分类、维度和混合账户尚未直接比较。我们通过验证性因子分析、潜在类别分析、探索性因子混合分析和探索性结构方程模型分析，对 43093 名具有全国代表性的个体的七种内在障碍进行了建模。二维（痛苦-恐惧）缺陷结构最适合，并且在性别、评估波次和终生/12 个月诊断中具有可重复性。这些缺陷，而不是特定于障碍的变异，预测了未来的内在病理、自杀企图、心绞痛和溃疡。
