腹腔神经丛阻滞对心率变异性的影响。
The effect of celiac plexus block on heart rate variability.
机构信息
Multidisciplinary Pain Centre, Aichi Medical University, School of Medicine, 21 Karimata, Nagakutecho, Aichigun, Nagakute, Aichi, 480-1195, Japan.
出版信息
J Anesth. 2013 Feb;27(1):62-5. doi: 10.1007/s00540-012-1467-6. Epub 2012 Aug 22.
BACKGROUND
Celiac plexus block (CPB) can be used for treating intra-abdominal visceral pain syndromes. The celiac plexus is the largest plexus of the sympathetic nervous system. Several nerve blocks have a marked effect on autonomic nervous activity. Furthermore, stellate ganglion block changes cardiac autonomic nervous activity. Thus, CPB could influence the sympathetic activity of the cardiac plexus. The aim of the present study was to see whether CPB modulated heart rate variability (HRV) in patients with pancreatic cancer.
METHODS
Twelve patients received neurolytic CPB using 14 ml absolute alcohol. Data recorded in a palm-sized electrocardiographic unit were analyzed for HRV.
RESULTS
CPB using a neurolytic solution did not induce any significant changes in the low-frequency (LF)/high-frequency (HF) ratio of HRV (LF/HF, P = 0.4642). Furthermore, the procedure did not induce any significant changes in blood pressure (systolic, P = 0.5051; diastolic, P = 0.5180).
CONCLUSION
CPB did not induce any significant changes in HRV or hemodynamics.
背景
腹腔神经丛阻滞（CPB）可用于治疗内脏疼痛综合征。腹腔神经丛是交感神经系统中最大的神经丛。一些神经阻滞对自主神经活动有明显的影响。此外，星状神经节阻滞可改变心脏自主神经活动。因此，CPB 可能会影响心脏丛的交感神经活动。本研究的目的是观察 CPB 是否会调节胰腺癌患者的心率变异性（HRV）。
方法
12 例患者接受 14ml 无水酒精的神经溶解 CPB。使用手掌大小的心电图仪记录的数据用于分析 HRV。
结果
CPB 使用神经溶解溶液不会引起 HRV 中低频（LF）/高频（HF）比值的任何显著变化（LF/HF，P=0.4642）。此外，该过程不会引起血压（收缩压，P=0.5051；舒张压，P=0.5180）的任何显著变化。
结论
CPB 不会引起 HRV 或血液动力学的任何显著变化。
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