Department of Otolaryngology, The New York Eye and Ear Infirmary, New York, New York, USA.
Head Neck. 2013 Jul;35(7):E205-8. doi: 10.1002/hed.23002. Epub 2012 Aug 21.
Paragangliomas are rare, vascular, and predominantly benign neoplasms of neural crest origin. They typically arise in the head and neck from the carotid body, jugulotympanic, or vagal paraganglia. Rarely, paragangliomas occur in the larynx. Only 2 cases of hypopharyngeal paraganglioma have been reported. We discuss the case of a hypopharyngeal paraganglioma and review the literature concerning laryngopharyngeal paragangliomas.
We present the case of a woman with 2 months of dysphagia and hoarseness that was found to have a hypopharyngeal paraganglioma. The patient underwent embolization and resection of the mass via a lateral thyrotomy approach. Pathologic analysis and selective staining confirmed the presence of a paraganglioma.
Proper histopathologic identification of these tumors is tantamount to guiding treatment. The preferred operative approach is a lateral thyrotomy to minimize patient morbidity. We present the third documented case of a hypopharyngeal paraganglioma and the first in the English-language literature.
副神经节瘤是一种罕见的、血管源性的、主要来源于神经嵴的良性肿瘤。它们通常起源于头颈部的颈动脉体、颈鼓室或迷走神经副神经节。副神经节瘤在喉部很少见。仅报道过 2 例下咽副神经节瘤。我们讨论了一例下咽副神经节瘤，并复习了有关喉咽副神经节瘤的文献。
我们介绍了一例女性患者，有 2 个月的吞咽困难和声音嘶哑，发现患有下咽副神经节瘤。患者接受了栓塞和通过侧甲状腺切开术切除肿块。病理分析和选择性染色证实存在副神经节瘤。
这些肿瘤的正确组织病理学鉴定对于指导治疗至关重要。首选的手术方法是侧甲状腺切开术，以最大限度地降低患者的发病率。我们提出了第三例下咽副神经节瘤的病例，也是英语文献中的首例。
