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丹麦百岁老人中心血管疾病的报告率很低。

Cardiovascular diseases are largely underreported in Danish centenarians.

机构信息

Department of Epidemiology, Institute of Public Health, University of Southern Denmark, Odense C, Denmark.

出版信息

Age Ageing. 2013 Mar;42(2):249-53. doi: 10.1093/ageing/afs108. Epub 2012 Aug 19.

Abstract

BACKGROUND

the substantial decline in oldest old mortality has led to more people surviving to very old age. As morbidity and disability generally increases with age epidemiological research in ageing has focused on the health of oldest olds. However, most studies are based on self-reported or physician-reported information, not objective health information.

OBJECTIVE

to estimate and compare the prevalence of cardiovascular diseases (CVDs) in Danish centenarians using three different sources of information: self-reported, physician-reported and objective data.

DESIGN

the population-based clinical-epidemiological study of 100-year-old Danes.

METHODS

all eligible participants were interviewed (self-report) in their domicile and offered a clinical examination, including an electrocardiogram (ECG) and blood pressure measurement. Further health information was retrieved from general practitioners' medical files and the Danish National Discharge Register (physician report).

RESULTS

out of 276 eligible, 207 (75%) participated. Blood pressure and ECG were measured in 76 and 69%, respectively. There was poor agreement between self-reported and physician-reported CVDs, and between physician-reported CVDs and clinical objective CVD diagnoses. Only angina pectoris reached a Kappa value of 0.5. ECG revealed twice as many cases of myocardial infarction and ischaemia compared with physician-reported. Using both physician-reported and ECG 95 (46%) of the centenarians suffered from at least one of the diseases myocardial infarction, angina pectoris or atrial fibrillation. Adding physician-reported heart failure and hypertension increased the prevalence of CVD to 80%.

CONCLUSION

self-reported information largely underestimates the CVD life-time prevalence in Danish centenarians. Objective clinical examinations are necessary to evaluate true disease prevalence in oldest old.

摘要

背景

最年长人群死亡率的大幅下降导致更多人能够活到非常高龄。由于发病率和残疾率通常随着年龄的增长而增加,衰老的流行病学研究一直集中在最年长人群的健康上。然而,大多数研究都是基于自我报告或医生报告的信息,而不是客观的健康信息。

目的

使用三种不同的信息来源(自我报告、医生报告和客观数据)来估计和比较丹麦百岁老人的心血管疾病(CVDs)患病率。

设计

基于人群的丹麦百岁老人临床流行病学研究。

方法

所有符合条件的参与者都在他们的住所接受了访谈(自我报告),并接受了临床检查,包括心电图(ECG)和血压测量。进一步的健康信息从全科医生的医疗档案和丹麦国家出院登记处(医生报告)中检索。

结果

在 276 名符合条件的参与者中,有 207 名(75%)参与了研究。分别有 76%和 69%的参与者接受了血压和心电图测量。自我报告和医生报告的 CVDs 之间以及医生报告的 CVDs 和临床客观 CVD 诊断之间的一致性较差。只有心绞痛达到了 0.5 的 Kappa 值。与医生报告相比,心电图显示出两倍多的心肌梗死和缺血病例。使用医生报告和心电图,95 名(46%)百岁老人至少患有一种疾病,包括心肌梗死、心绞痛或心房颤动。如果加上医生报告的心力衰竭和高血压,CVD 的患病率将增加到 80%。

结论

自我报告的信息大大低估了丹麦百岁老人一生中 CVD 的患病率。客观的临床检查对于评估最年长人群的真实疾病患病率是必要的。

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