Department of Anesthesiology, University Leipzig, Heart Center, Struempellstrasse 39, D-04289 Leipzig, Germany.
Best Pract Res Clin Anaesthesiol. 2012 Jun;26(2):167-77. doi: 10.1016/j.bpa.2012.06.001.
In the last 10 years, implantation of ventricular-assist devices has become an interesting option as either bridge-to-transplantation or destination procedure for patients with end-stage congestive heart failure. In the future, the number of ventricular assist device implantations is expected to increase furthermore. In general, this patient cohort is associated with significant co-morbidities, for example, pulmonary hypertension, peripheral vascular disease and renal insufficiency. Anaesthetic management for implantation of ventricular assist devices can be challenging for cardiac anaesthesiologists. Even minor changes in their haemodynamics and physiological parameters can cause significant morbidity and mortality. Experience in haemodynamic monitoring including echocardiography and pharmacological management (use of inotropes, phosphodiesterase inhibitors and vasopressors) is a requirement. Particularly, the diagnosis and therapy of right-sided heart failure after implantation of left-ventricular assist devices should be addressed.
在过去的 10 年中,心室辅助装置的植入已成为一种很有前途的选择,可作为移植前的桥接治疗,或作为终末期充血性心力衰竭患者的治疗方法。未来,心室辅助装置的植入数量预计还会进一步增加。一般来说,这一患者群体伴有明显的合并症,例如肺动脉高压、外周血管疾病和肾功能不全。对于植入心室辅助装置的患者,心脏麻醉医师的麻醉管理可能具有挑战性。即使其血液动力学和生理参数发生微小变化,也可能导致显著的发病率和死亡率。对包括超声心动图在内的血液动力学监测和药理学管理(使用正性肌力药、磷酸二酯酶抑制剂和血管加压药)的经验是必要的。特别是,在植入左心室辅助装置后,应诊断和治疗右心衰竭。