Méndez Gutiérrez T H, Dehesa Violante M, Rodríguez Jerkov J, de la Garza S, González Loya F
Servicio de Gastroenterología, Hospital de Especialidades, México, D.F.
Rev Gastroenterol Mex. 1990 Jan-Mar;55(1):13-5.
The histopathological study is very useful to establish a correct diagnosis in hepatic diseases, nevertheless conventional percutaneous liver biopsy is contraindicated in patients with abnormal coagulation. For this reason, some other alternatives have been looked for. The purpose of this study was to evaluate the safety and effectivity of gelfoam plugged liver biopsy, like alternative of the conventional biopsy in patients with impaired coagulation. The procedure was done in fourteen patients with prothrombin time longer than twelve seconds over the control and platelet count until 20,000/mm3. Besides that, we used real time ultrasound to guide the biopsy, in order to improve the safety and effectivity of this technique. All were successful, and there were no serious complications. This technique is a good alternative in patients with liver disease and impaired coagulation, in whom the histological diagnosis is essential.
组织病理学研究对于肝病的正确诊断非常有用，然而常规经皮肝活检在凝血功能异常的患者中是禁忌的。因此，人们一直在寻找其他替代方法。本研究的目的是评估明胶海绵栓塞肝活检的安全性和有效性，作为凝血功能受损患者常规活检的替代方法。该操作在14名凝血酶原时间比对照延长超过12秒且血小板计数低至20,000/mm³的患者中进行。此外，我们使用实时超声引导活检，以提高该技术的安全性和有效性。所有操作均成功，且无严重并发症。对于肝病且凝血功能受损且组织学诊断至关重要的患者，该技术是一种很好的替代方法。
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