非包膜 DNA 和 RNA 型病毒对光动力灭活的敏感性。
Susceptibility of non-enveloped DNA- and RNA-type viruses to photodynamic inactivation.
机构信息
Department of Biology and CESAM, University of Aveiro, 3810-193 Aveiro, Portugal.
出版信息
Photochem Photobiol Sci. 2012 Oct;11(10):1520-3. doi: 10.1039/c2pp25156f.
PMID:22911122
Abstract
The comparative susceptibility of DNA- and RNA-type viruses to photodynamic inactivation has not yet been clearly addressed. In this study the effect of the tricationic porphyrin Tri-Py(+)-Me-PF on the inactivation of four DNA and three RNA non-enveloped phages was compared. The results obtained show that the photodynamic efficiency varied with the phage type, the RNA-type phages being much more easily photoinactivated than the DNA-type ones.
摘要
DNA 型和 RNA 型病毒对光动力失活的相对敏感性尚未得到明确解决。在这项研究中，比较了三阳离子卟啉 Tri-Py(+)-Me-PF 对四种 DNA 和三种 RNA 非包膜噬菌体失活的影响。结果表明，光动力效率随噬菌体类型的不同而变化，RNA 型噬菌体比 DNA 型噬菌体更容易光灭活。
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