个性化医疗的综合框架：从个体基因组到参与式医疗保健。
An integrated framework of personalized medicine: from individual genomes to participatory health care.
作者信息
Evers Andrea W M, Rovers Maroeska M, Kremer Jan A M, Veltman Joris A, Schalken Jack A, Bloem Bas R, van Gool Alain J
机构信息
Department of Medical Psychology, Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands.
出版信息
Croat Med J. 2012 Aug;53(4):301-3. doi: 10.3325/cmj.2012.53.301.
Abstract
Promising research developments in both basic and applied sciences, such as genomics and participatory health care approaches, have generated widespread interest in personalized medicine among almost all scientific areas and clinicians. The term personalized medicine is, however, frequently used without defining a clear theoretical and methodological background. In addition, to date most personalized medicine approaches still lack convincing empirical evidence regarding their contribution and advantages in comparison to traditional models. Here, we propose that personalized medicine can only fulfill the promise of optimizing our health care system by an interdisciplinary and translational view that extends beyond traditional diagnostic and classification systems.
摘要
基础科学和应用科学领域（如基因组学和参与式医疗保健方法）中一些有前景的研究进展，在几乎所有科学领域和临床医生中引发了对个性化医疗的广泛兴趣。然而，“个性化医疗”一词在使用时，常常没有明确的理论和方法背景。此外，迄今为止，与传统模式相比，大多数个性化医疗方法在其贡献和优势方面仍缺乏令人信服的实证依据。在此，我们提出，个性化医疗只有通过一种超越传统诊断和分类系统的跨学科和转化视角，才能实现优化我们医疗保健系统的愿景。
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