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心脏移植患者中内皮细胞抗体介导的排斥反应和成功再移植。

Endothelial cell antibody-mediated rejection and successful retransplantation in a heart transplanted patient.

机构信息

Transplant Institute, Sahlgrenska University Hospital, University of Gothenburg, Gothenburg, Sweden.

出版信息

Eur J Cardiothorac Surg. 2012 Dec;42(6):1044-6. doi: 10.1093/ejcts/ezs368. Epub 2012 Aug 21.

Abstract

Antibody-mediated rejection (AMR) plays a significant role in cardiac allograft dysfunction, and recently a consensus regarding the diagnosis of AMR has been published. To our knowledge, it has not previously been reported that acute graft failure related to AMR, and antiendothelial cell antibodies can successfully be diagnosed to allow the patient to receive the outlined treatment and undergo a subsequent retransplantation.

摘要

抗体介导的排斥反应(AMR)在心脏移植物功能障碍中起着重要作用,最近已经发表了关于 AMR 诊断的共识。据我们所知,此前尚未有报道称与 AMR 相关的急性移植物衰竭可以成功诊断,并使患者接受规定的治疗和随后的再次移植。

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