Hess B
Policlinic of Medicine, University of Berne, Switzerland.
Urol Res. 1990;18 Suppl 1:S45-8. doi: 10.1007/BF00301528.
Lowering supersaturation with respect to struvite and carbonate apatite is the most important prophylactic measure in patients with infection-induced kidney stone disease. This is best achieved by combining culture-specific antibiotics with urinary acidification. Urinary infection with non-urease-producing Escherichia coli, probably promoting struvite particle formation, must be eradicated. Possible measures for improving urothelial anti-adherence properties or reducing bacterial adherence are discussed.