Temiz Tayfun, Yaylacı Selcuk, Demir Mustafa Volkan, Kahyaoglu Zeynep, Tamer Ali, Uslan Mustafa Ihsan
Department of Internal Medicine, Sakarya Education and Research Hospital, Sakarya, Turkey.
N Am J Med Sci. 2012 Aug;4(8):367-8. doi: 10.4103/1947-2714.99522.
Eosinophilic gastroenteritis (EGE) is a rare disease characterized by eosinophilic infiltration and peripheral eosinophilia. It can be seen anywhere in the gastrointestinal tract. It is diagnosed in the biopsies taken during endoscopic examination to the patients with abdominal pain and chronic diarrhea. A 40-year-old woman was admitted with abdominal pain and chronic diarrhea. She has not any disease, food, pollen, or drug allergy in her medical history. Leukocyte: 19,400/mm3 (neutrophil: 19.9%, eosinophil: 57.4%, lymphocyte: 16.5%), platelet: 281,000/ mm(3), immunoglobulin E: 1721 IU/mL (normal range: 20-100 IU/mL) was counted in her blood examination. The duodenal biopsy was reported as EGE. We applied methylprednisolone 20 mg/day. With this treatment, the patient's symptoms regressed. In this article we present a case of chronic diarrhea diagnosed EGE. The first step in diagnosing is suspecting EGE. It should be borne in mind in patients with chronic diarrhea.
嗜酸性粒细胞性胃肠炎（EGE）是一种罕见疾病，其特征为嗜酸性粒细胞浸润和外周血嗜酸性粒细胞增多。它可发生于胃肠道的任何部位。对于有腹痛和慢性腹泻的患者，通过内镜检查时获取的活检组织进行诊断。一名40岁女性因腹痛和慢性腹泻入院。她既往病史中无任何疾病、食物、花粉或药物过敏史。血液检查显示白细胞：19,400/mm³（中性粒细胞：19.9%，嗜酸性粒细胞：57.4%，淋巴细胞：16.5%），血小板：281,000/mm³，免疫球蛋白E：1721 IU/mL（正常范围：20 - 100 IU/mL）。十二指肠活检报告为EGE。我们给予甲泼尼龙20 mg/天。经此治疗，患者症状缓解。在本文中，我们呈现一例诊断为EGE的慢性腹泻病例。诊断的第一步是怀疑EGE。对于慢性腹泻患者应予以考虑。
