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[麦角中毒——肢体急性缺血的罕见病因]

[Ergotism--a rare cause of acute ischemia of the extremities].

作者信息

Erasmi H, Schmidt R, Walter M, Gross-Fengels W

机构信息

Chirurgische Klinik und Poliklinik, Universität Köln.

出版信息

Vasa. 1990;19(4):279-85.

PMID:2291306
Abstract

Clinical ergotism as seen today results almost exclusively from the excessive intake of ergotamine tartrate in the treatment of migraine headache. Vasospasm of peripheral arteries is the leading clinical picture. Beside formation of collaterals and secondary thrombosis, vasospasm is one of the specific findings in angiography. Early diagnosis and withdrawal of the medication makes complete restitution possible. In all other cases intraarterial or intravenous infusion of sodium nitroprusside or nitroglycerin has turned out to be the most effective therapy. Balloon dilatation or operative intervention are an alternative therapy in those cases, where amputation of the limb seems to be necessary.

摘要

如今所见的临床麦角中毒几乎完全是由于在治疗偏头痛时过量摄入酒石酸麦角胺所致。外周动脉血管痉挛是主要的临床表现。除了侧支形成和继发性血栓形成外,血管痉挛是血管造影的特异性表现之一。早期诊断并停用药物可实现完全恢复。在所有其他情况下,动脉内或静脉内输注硝普钠或硝酸甘油已被证明是最有效的治疗方法。在那些似乎有必要截肢的病例中,球囊扩张或手术干预是一种替代疗法。

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