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[大鼠结肠在大肠梗阻及其缓解后血液微循环床血管的形态计量学特征]

[Morphometric characteristics of the hemomicrocirculatory bed vessels in rat colon in large bowel obstruction and after its resolution].

作者信息

Gaĭvoronskiĭ I V, Petrov A S, Sotnikov A S

出版信息

Morfologiia. 2012;141(2):35-9.

Abstract

The results are presented that describe the experimental study of colonic hemomicrocirculatory bed (HMCB) in intact rats, in animals 6 days after large bowel obstruction development that was modeled using the device created by the authors, and 1-15 days after its resolution. The most significant changes were observed in the capillaries and HMCB venular portion--capillary diameter was increased by 60-100%, while that of venules--by 73% as compared to those in control group. The degree of changes depended on the distance from the extraorgan bowel compression site. The dynamics of the normalization of morphometric parameters after colon obstruction resolution was demonstrated. It was found that the average arteriolar and venular diameters reached the initial level by day 5, while that of the capillaries by day 7 after colon obstruction resolution.

摘要

研究结果描述了对完整大鼠结肠血液微循环床(HMCB)的实验研究,该研究涵盖了在使用作者自制装置模拟大肠梗阻形成后6天的动物,以及梗阻解除后1 - 15天的动物。在毛细血管和HMCB的小静脉部分观察到了最显著的变化——与对照组相比,毛细血管直径增加了60 - 100%,小静脉直径增加了73%。变化程度取决于距器官外肠管压迫部位的距离。展示了结肠梗阻解除后形态计量学参数的归一化动态过程。结果发现,结肠梗阻解除后,小动脉和小静脉的平均直径在第5天达到初始水平,而毛细血管的平均直径在第7天达到初始水平。

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