Golubev A M, Magomedov M A, Leont'eva T A, Guseĭnov T S
Morfologiia. 1996;109(3):36-40.
Dynamics of biomicroscopic state of hemomicrocirculatory bed (HMCB) of small intestinal mesentery was studied in go both sexes albino outbred rats in conditions of intravenous administration of 1.0 ml perfuoram (PF) with simultaneous control of the experiment by intravenous isotonic solution administration. Biomicroscopy was performed 30 minutes, 3, 6 and 24 hours later. 30 minutes after the PF administration bloodflow reduction in afferent vessels, elongation of construction period of resistant vessels and 18% decrease of vessels were demonstrated. Precapillary diameter decreased on 23% with respect to control with isotonic solution. Tortuosity of precapillaries and decrease of functioning capillaries number. 3 hours after the PF infusion blood flow turned more slow, signs of adhesion between leukocytes and postcapillary venules lumenal surface appeared and perivascular infiltrate had formed. Diameter of alducent vessels reduced in comparison with control and went lugher against the 30-minutes research stage. On the whole bloodflow in resistant vessels turns homogeneous. 6 hours after PF infusion homogeneous bloodflow could be seen. Number of arteriolar vasomotions grew up to control and made 14 in a minute. Venular diameter was close to control. Biomicroscopy of HMCB 24 hours after infusion did not reveal essential differences compared to with isotonic solution administered.
在向雌雄白化远交系大鼠静脉注射1.0毫升全氟碳（PF）的条件下，同时通过静脉注射等渗溶液作为实验对照，研究了小肠系膜血液微循环床（HMCB）的生物显微镜状态变化。在注射PF后30分钟、3小时、6小时和24小时进行生物显微镜检查。注射PF后30分钟，发现传入血管血流减少，阻力血管的收缩期延长，血管数量减少18%。与注射等渗溶液的对照组相比，毛细血管前直径减小了23%。毛细血管迂曲，功能性毛细血管数量减少。注射PF 3小时后，血流变得更缓慢，白细胞与毛细血管后微静脉管腔表面出现粘连迹象，并形成血管周围浸润。与对照组相比，引流血管直径减小，与注射后30分钟的研究阶段相比有所增加。总体而言，阻力血管中的血流变得均匀。注射PF 6小时后，可见均匀的血流。小动脉血管运动次数增加至对照组水平，每分钟14次。微静脉直径接近对照组。注射24小时后HMCB的生物显微镜检查与注射等渗溶液相比未发现明显差异。
