Vyzhigina M A, Luk'ianov M V, Nazarov B F, Titov V A, Krivitskiĭ N M
Vestn Akad Med Nauk SSSR. 1990(12):45-50.
The hemodynamic effects of different modes of controlled ventilation (CV) were studied by means of impedance plethysmography in 52 anesthetized patients during surgery on the lungs, trachea, and bronchi. To adapt this investigation technique to the conditions of the operating room, a specially designed device was applied for extracorporeal measurement of electric resistance of the blood flow. It was found that impaired transcapillary exchange of fluid in the lungs and its accumulation in the interstitial spaces were secondary to the operated lung collapse irrespective of the composition of the inhaled gas mixture used for the controlled ventilation of the contralateral lung. A differential approach to the ventilation of the dependent and independent lungs using the conventional and high-frequency CV modifications allows for an optimal compensation for the damaged transcapillary exchange of fluids in the lungs, is most physiological, sparing, and organ-saving.
通过阻抗体积描记法，对52例接受肺、气管和支气管手术的麻醉患者在不同控制通气（CV）模式下的血流动力学效应进行了研究。为使该研究技术适应手术室环境，采用了一种专门设计的装置用于体外测量血流电阻。结果发现，无论用于对侧肺控制通气的吸入气体混合物成分如何，肺部毛细血管间液体交换受损及其在间质间隙的积聚均继发于手术侧肺萎陷。采用传统和高频CV改良方法对依赖肺和非依赖肺进行差异通气，可对肺部受损的毛细血管间液体交换进行最佳补偿，最为生理、节能且对器官有保护作用。
