Holschneider A M, Schlachtenrath R, Knoop U
Kinderchirurgische Klinik, Kinderkrankenhauses der Stadt Köln.
Z Kinderchir. 1990 Dec;45(6):349-59. doi: 10.1055/s-2008-1042614.
101 patients were subjected to partial lung resection from 1962-1969 at the Division of Paediatric Surgery in the Department of Paediatrics of the University of Cologne. Follow-up examinations were performed in 38 patients. 24 patients were entirely without complaints, 9 had mild subjective complaints, and only 5 patients stated they were suffering continually from dyspnoea. Lung function tests were conducted in all patients, revealing a significant drop in vital capacity as the number of resected segments increased. The intrathoracic gas volume expressed in percentage of the standard value increased significantly with the number of resected segments. The flow volume curves dropped with the number of resected segments, whereas the airway resistance increased. These studies show that lung resections are not always tolerated without restricted function even by children. Hence, lung resection should be performed with utmost discretion and only if absolutely necessary. This is all the more important since adjacent pulmonary tissue may also be involved in the pathological process due to the underlying disease.
1962年至1969年期间，科隆大学儿科学系小儿外科对101例患者进行了部分肺切除术。对38例患者进行了随访检查。24例患者完全没有不适，9例有轻微的主观不适，只有5例患者表示他们持续存在呼吸困难。对所有患者进行了肺功能测试，结果显示随着切除肺段数量的增加，肺活量显著下降。以标准值百分比表示的胸腔内气体量随着切除肺段数量的增加而显著增加。流量容积曲线随着切除肺段数量的增加而下降，而气道阻力增加。这些研究表明，即使是儿童，肺切除术后也并非总能在功能不受限的情况下耐受。因此，肺切除术应极其谨慎地进行，且仅在绝对必要时进行。这一点尤为重要，因为由于潜在疾病，相邻的肺组织也可能参与病理过程。
