Nihon University Graduate School of Dentistry at Matsudo, Chiba, Japan.
J Dent Res. 2012 Nov;91(11):1043-8. doi: 10.1177/0022034512458925. Epub 2012 Aug 20.
To determine the amount of 10-methacryloyloxydecyl dihydrogen phosphate (MDP)-calcium (MDP-Ca) salt produced through the demineralization of enamel or dentin by MDP, we designed experimental MDP-based one-step adhesives with different amounts of MDP. The null hypotheses were that (1) the amount of MDP-Ca salt produced through the demineralization of enamel was the same as that for dentin, and (2) the amounts of MDP-Ca salt have no effect on bonding performance. Increases in the amount of MDP resulted in increased amounts of MDP-Ca salt. The production amount of MDP-Ca salt of the dentin was 1.3 times higher than that of the enamel. The predominant species of the MDP and enamel reactants was a calcium hydrogen phosphate of MDP. In contrast, the dentin yielded both calcium phosphate and calcium hydrogen phosphate of MDP. Increases in the amount of MDP-Ca salt decreased both enamel and dentin bond strengths. An optimal concentration of MDP exists in one-step self-etch adhesives.
为了确定通过 MDP 脱矿作用产生的 10-甲基丙烯酰氧癸基二氢磷酸酯（MDP）-钙（MDP-Ca）盐的量，我们设计了具有不同 MDP 含量的基于 MDP 的实验性一步法胶粘剂。零假设是：（1）通过脱矿作用产生的 MDP-Ca 盐的量与牙本质相同，（2）MDP-Ca 盐的量对粘结性能没有影响。MDP 含量的增加导致 MDP-Ca 盐的含量增加。牙本质产生的 MDP-Ca 盐量是牙釉质的 1.3 倍。MDP 和牙釉质反应物的主要物质是 MDP 的磷酸氢钙。相比之下，牙本质既产生 MDP 的磷酸钙又产生 MDP 的磷酸氢钙。MDP-Ca 盐含量的增加降低了牙釉质和牙本质的粘结强度。一步自酸蚀胶粘剂中存在最佳的 MDP 浓度。
