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数字减影脊髓造影在自发性脊柱脑脊液漏的诊断和定位中的作用。

The role of digital subtraction myelography in the diagnosis and localization of spontaneous spinal CSF leaks.

机构信息

Department of Radiology, Mayo Clinic, Phoenix, AZ 85054, USA.

出版信息

AJR Am J Roentgenol. 2012 Sep;199(3):649-53. doi: 10.2214/AJR.11.8238.

Abstract

OBJECTIVE

The objective of our study was to review the clinical utility of digital subtraction myelography for the diagnosis of spinal CSF leaks in patients with spontaneous intracranial hypotension (SIH) and those with superficial siderosis.

MATERIALS AND METHODS

Procedure logs from 2007 to 2011 were reviewed to identify cases in which digital subtraction myelography was performed to diagnose spinal CSF leaks. Electronic medical records were reviewed to obtain information regarding diagnosis and outcome. For patients to be included in the study, preprocedural spinal MRI had to show an extradural fluid collection spanning more than one vertebral level and postmyelographic CT had to confirm the presence of an active CSF leak. If digital subtraction myelography successfully showed the site of the CSF leak, the location was documented.

RESULTS

Eleven patients (seven men and four women; mean age, 49.0 years) underwent digital subtraction myelography during the study period. Six patients had SIH and five patients had superficial siderosis. The extradural fluid collection on spinal MRI averaged a length of 15.5 vertebral levels. Digital subtraction myelography successfully showed the site of the CSF leak in nine of the 11 patients, and all of the dural tears were located in the thoracic spine between T3 and T11.

CONCLUSION

Digital subtraction myelography is a valuable diagnostic tool for the localization of rapid spinal CSF leaks and should be considered in patients who are clinically suspected to have a dural tear that is accompanied by a longitudinally extensive extradural fluid collection on spinal MRI.

摘要

目的

我们研究的目的是回顾数字减影脊髓造影在自发性颅内低血压(SIH)和表浅性铁沉着症患者中诊断脊髓脑脊液漏的临床应用。

材料与方法

回顾 2007 年至 2011 年的程序日志,以确定进行数字减影脊髓造影以诊断脊髓脑脊液漏的病例。查阅电子病历以获取有关诊断和结果的信息。为了使患者纳入研究,术前脊髓 MRI 必须显示跨越多个椎体水平的硬膜外积液,且脊髓造影后 CT 必须证实存在活跃的脑脊液漏。如果数字减影脊髓造影成功显示脑脊液漏的部位,则记录其位置。

结果

在研究期间,11 例患者(7 例男性,4 例女性;平均年龄 49.0 岁)接受了数字减影脊髓造影。6 例患者为 SIH,5 例患者为表浅性铁沉着症。脊髓 MRI 上的硬膜外积液平均长度为 15.5 个椎体水平。11 例患者中有 9 例数字减影脊髓造影成功显示了脑脊液漏的部位,所有的硬脑膜撕裂均位于 T3 至 T11 之间的胸段脊柱。

结论

数字减影脊髓造影是快速脊髓脑脊液漏定位的有价值的诊断工具,对于临床上怀疑有硬脑膜撕裂且脊髓 MRI 上有广泛的硬膜外积液的患者,应考虑使用该方法。

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