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冠状动脉搭桥手术后的钙过敏:伤口并发症的一个未被充分认识的原因?

Calciphylaxis following coronary artery bypass surgery: an underappreciated cause of wound complications?

作者信息

Firstenberg Michael S, Tripathi Ravi S, Grose Noah A, Abel Erik, Peters Sara B, Papadimos Thomas J

机构信息

Department of Surgery, The Ohio State University Medical Center, Columbus, OH, USA.

出版信息

Heart Surg Forum. 2012 Aug;15(4):E218-20. doi: 10.1532/HSF98.20121024.

Abstract

Wound complications following cardiac surgery are typically infectious and associated with a high morbidity and mortality. Calciphylaxis, vascular calcification of small and medium sized vessels, often associated with end-stage renal disease, can result in extensive tissue necrosis. We hypothesize that calciphylaxis is an under-recognized and under-reported precipitating wound and breast complication following coronary artery bypass surgery and thereby necessitates further study.

摘要

心脏手术后的伤口并发症通常具有感染性,且与高发病率和死亡率相关。钙化防御,即中小血管的血管钙化,通常与终末期肾病有关,可导致广泛的组织坏死。我们推测,钙化防御是冠状动脉搭桥手术后一种未被充分认识和报道的伤口及乳房并发症的诱发因素,因此有必要进一步研究。

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