Department of Chemistry, University of Kalyani, Kalyani, West Bengal, India.
J Colloid Interface Sci. 2012 Nov 15;386(1):9-15. doi: 10.1016/j.jcis.2012.06.073. Epub 2012 Jul 16.
This work outlines a novel method for the synthesis of stable gold nanoparticles within the spatially confined region of vesicles. For the first time, Span/cholesterol based niosomes have been used for nanoparticle synthesis. The restricted geometry within niosomes prevents nanoparticle aggregation. The results have important implications for controlled delivery of nanoparticles for therapeutic applications.
这项工作概述了一种在囊泡的空间受限区域内合成稳定金纳米粒子的新方法。首次使用基于 Span/胆固醇的非离子型脂质体来合成纳米粒子。非离子型脂质体的受限几何形状可防止纳米粒子聚集。这些结果对于控制纳米粒子的递送来实现治疗应用具有重要意义。