CAS Key Laboratory of Soft Matter Chemistry, Department of Chemistry, University of Science and Technology of China, Hefei, Anhui 230026, China.
Langmuir. 2011 Aug 16;27(16):9666-70. doi: 10.1021/la201617p. Epub 2011 Jul 25.
Nanoparticles that respond to various chemical and physical stimuli form the basis for various conceivable applications including sensors, chemical logic, biomedical imaging, and therapies. In this work, we demonstrate that the electrostatic and chemical (complexing and gold-thiol bonding) interactions existing in a gold nanoparticle/Zn(2+)/dithiothreitol-based ternary chemical system is "programmable" and can be utilized to regulate the aggregation and dispersion of nanoparticles via XOR and INHIBIT logics. The resulting solutions alter their colors according to different input combinations because of the well-controlled aggregation or dispersion of plasmonic gold nanoparticles, opening up new possibilities for the developments of advanced sensors and nanobiomedical devices based on the coupling, gating, and signaling of different chemical stimuli.
纳米粒子可以响应各种化学和物理刺激，这为各种可以想象的应用奠定了基础，包括传感器、化学逻辑、生物医学成像和治疗。在这项工作中，我们证明了存在于金纳米粒子/Zn(2+)/二硫苏糖醇基三元化学体系中的静电和化学（络合和金-硫醇键合）相互作用是“可编程”的，并可通过 XOR 和 INHIBIT 逻辑来调节纳米粒子的聚集和分散。由于等离子体金纳米粒子的聚集或分散得到了很好的控制，所得溶液会根据不同的输入组合改变颜色，为基于不同化学刺激的耦合、门控和信号传递的先进传感器和纳米生物医学设备的发展开辟了新的可能性。
