Fouladi D Behzad, Nassiri Parvin, Monazzam E Mohammadreza, Farahani Saeed, Hassanzadeh Gholamreza, Hoseini Mostafa
Department of Occupational Health, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Noise Health. 2012 Jul-Aug;14(59):184-9. doi: 10.4103/1463-1741.99894.
Measuring non-auditory effects of noise such as stress-inducing ones have become of interest recently. Salivary cortisol has become a popular measure in stress research. So, assessing noise-induced stress via saliva cortisol evaluation can present a bright future in non-invasive exposure assessment methods. This study had 3 goals: (1) Assess and compare saliva cortisol concentrations in the morning and evening in normal work day and leisure day in industrial workers, (2) assess the relationship between industrial noise exposure and salivary cortisol concentrations, and (3) assess the possibility of using salivary cortisol as a possible marker of noise-induced stress. This study included 80 male participants working in 4 different parts (painting, assembling lines, casting, and packaging) of a household manufacturing company. Morning and evening saliva samples were collected at 7.00 am and 4.00 pm, respectively. Noise exposure levels were assessed by sound level meter and noise dosimeter. All measurements occurred in two days: One in leisure day and other in working day. Descriptive statistics, paired sample t-test, and regression analysis were used as statistical tools of this study with P < 0.05. On the leisure day, morning salivary cortisol (geometric mean [GM], 15.0; 95% CI, 12.0 to 19.0 nmol/L) was significantly higher than evening cortisol (GM, 5.2; 95% CI, 4.2 to 6.3 nmol/L) (P < 0.05). Also, on the working day, morning salivary cortisol (GM, 14.0; 95% CI, 11.25 to 18.0 nmol/L) was significantly higher than evening cortisol (GM, 8.0; 95% CI, 6.5 to 10.0 nmol/L) (P < 0.05). No significant difference was obtained for morning cortisol levels between leisure day and working day samples (P = 0.117). But, for evening cortisol concentrations, a strong significant difference was noted leisure day and working day (P < 0.001). The evening cortisol in the working day correlated significantly with noise exposure > 80 dBA. Our study revealed that industrial noise, with levels > 80 dBA, has a significant effect on salivary cortisol elevation.
测量噪声的非听觉效应，如诱导压力的效应，近来已受到关注。唾液皮质醇已成为压力研究中一种常用的测量指标。因此，通过唾液皮质醇评估来测定噪声诱发的压力，在无创暴露评估方法方面前景光明。本研究有3个目标：（1）评估并比较产业工人正常工作日和休息日早晚的唾液皮质醇浓度；（2）评估产业噪声暴露与唾液皮质醇浓度之间的关系；（3）评估将唾液皮质醇用作噪声诱发压力可能标志物的可能性。本研究纳入了80名在一家家用制造公司4个不同部门（喷漆、装配线、铸造和包装）工作的男性参与者。分别于上午7:00和下午4:00采集早晚的唾液样本。通过声级计和噪声剂量计评估噪声暴露水平。所有测量均在两天内进行：一天是休息日，另一天是工作日。描述性统计、配对样本t检验和回归分析被用作本研究的统计工具，P<0.05。在休息日，上午唾液皮质醇（几何均值[GM]，15.0；95%置信区间，12.0至19.0 nmol/L）显著高于晚上的皮质醇（GM，5.2；95%置信区间，4.2至6.3 nmol/L）（P<0.05）。同样，在工作日，上午唾液皮质醇（GM，14.0；95%置信区间，11.25至18.0 nmol/L）显著高于晚上的皮质醇（GM，8.0；95%置信区间，6.5至10.0 nmol/L）（P<0.05）。休息日和工作日样本的上午皮质醇水平未获得显著差异（P = 0.117）。但是，对于晚上的皮质醇浓度，休息日和工作日之间存在强烈的显著差异（P<0.001）。工作日的晚上皮质醇与>80 dBA的噪声暴露显著相关。我们的研究表明，>80 dBA的产业噪声对唾液皮质醇升高有显著影响。
