Department of Surgery, Academic Medical Center, Amsterdam, Netherlands.
Br J Radiol. 2012 Sep;85(1017):1255-62. doi: 10.1259/bjr/88405305.
To obtain diagnostic performance values of CT, MRI, ultrasound and 18-fludeoxyglucose positron emission tomography (PET)/CT for staging of hilar cholangiocarcinoma.
A comprehensive systematic search was performed for articles published up to March 2011 that fulfilled the inclusion criteria. Study quality was assessed with the quality assessment of diagnostic accuracy studies tool.
16 articles (448 patients) were included that evaluated CT (n=11), MRI (n=3), ultrasound (n=3), or PET/CT (n=1). Overall, their quality was moderate. The accuracy estimates for evaluation of CT for ductal extent of the tumour was 86%. The sensitivity and specificity estimates of CT were 89% and 92% for evaluation of portal vein involvement, 83% and 93% for hepatic artery involvement, and 61% and 88% for lymph node involvement, respectively. Data were too limited for adequate comparisons of the different techniques.
Diagnostic accuracy studies of CT, MRI, ultrasound or PET/CT for staging of hilar cholangiocarcinoma are sparse and have moderate methodological quality. Data primarily concern CT, which has an acceptable accuracy for assessment of ductal extent, portal vein and hepatic artery involvement, but low sensitivity for nodal status.
获取 CT、MRI、超声和 18 氟脱氧葡萄糖正电子发射断层扫描（PET）/CT 对肝门部胆管癌分期的诊断性能值。
对截至 2011 年 3 月符合纳入标准的文献进行全面系统检索。使用诊断准确性研究质量评估工具评估研究质量。
共纳入 16 篇文章（448 例患者），评估 CT（n=11）、MRI（n=3）、超声（n=3）或 PET/CT（n=1）。总体而言，其质量为中等。评估肿瘤管腔范围的 CT 准确性估计值为 86%。CT 评估门静脉受累的敏感性和特异性估计值分别为 89%和 92%，肝动脉受累为 83%和 93%，淋巴结受累为 61%和 88%。数据对于充分比较不同技术来说太有限了。
对肝门部胆管癌分期的 CT、MRI、超声或 PET/CT 的诊断准确性研究很少，且具有中等的方法学质量。数据主要涉及 CT，其对胆管范围、门静脉和肝动脉受累的评估具有可接受的准确性，但对淋巴结状态的敏感性较低。
