Valent-Morić Bernardica, Zigman Tamara, Zaja-Franulović Orjena, Malenica Masa, Cuk Martin
University Department of Pediatrics, Sestre milosrdnice University Hospital Center, Zagreb, Croatia.
Acta Clin Croat. 2012 Mar;51(1):59-64.
The objective of this study was to present our data on ambulatory blood pressure monitoring (ABPM) in children and adolescents referred to our Department because of casual BP elevation over the 95th percentile on at least 3 visits in primary care office. ABPM studies in 139 children, 94 boys and 45 girls, mean age 14.14 (range 4-19) years, were reviewed. A total of 107 (76.98%) children had hypertension according to the ABPM criteria. Primary hypertension (PH) was diagnosed in 89 (64.03%), secondary hypertension (SH) in 18 (12.95%) and white coat hypertension (WCH) in 32 (23.02%) children. In both PH and SH groups, hypertension was predominantly systolic (60.67% and 55.56%, respectively). There was no statistically significant difference in diurnal and nocturnal systolic and diastolic blood pressure (BP) loads between PH and SH groups. The non-dipping phenomenon was detected in 49.44%, 66.66% and 40.62% of children with PH, SH and WCH, respectively. The mean pulse pressure values were 60.41, 58.58 and 52.25 mm Hg in the PH, SH and WCH groups, respectively. A statistically significant difference was found in pulse pressure values between PH and WCH (df=55, t=6.15, P<0.01) groups and between SH and WCH groups (df=31, t=3.18, P=0.001). Target organ damage was diagnosed in 16 (17.98%) children with PH and in 5 (27.78%) children with SH. None of the children with WCH had target organ damage. ABPM is indispensable for establishing the diagnosis of hypertension in children. It is the only reliable method of WCH diagnosis.
本研究的目的是呈现我们对因在基层医疗诊所至少3次就诊时偶然血压升高超过第95百分位数而转诊至我科的儿童和青少年进行动态血压监测(ABPM)的数据。回顾了对139名儿童(94名男孩和45名女孩)进行的ABPM研究,平均年龄14.14岁(范围4 - 19岁)。根据ABPM标准,共有107名(76.98%)儿童患有高血压。原发性高血压(PH)在89名(64.03%)儿童中被诊断出,继发性高血压(SH)在18名(12.95%)儿童中被诊断出,白大衣高血压(WCH)在32名(23.02%)儿童中被诊断出。在PH组和SH组中,高血压主要为收缩期高血压(分别为60.67%和55.56%)。PH组和SH组之间的日间和夜间收缩压及舒张压负荷无统计学显著差异。分别在49.44%、66.66%和40.62%的PH、SH和WCH儿童中检测到非勺型现象。PH组、SH组和WCH组的平均脉压值分别为60.41、58.58和52.25 mmHg。在PH组和WCH组之间(自由度 = 55,t = 6.15,P < 0.01)以及SH组和WCH组之间(自由度 = 31,t = 3.18,P = 0.001)发现脉压值存在统计学显著差异。在16名(17.98%)PH儿童和5名(27.78%)SH儿童中诊断出靶器官损害。WCH儿童中无一例有靶器官损害。ABPM对于儿童高血压的诊断不可或缺。它是WCH诊断的唯一可靠方法。