由丝聚合蛋白（FLG）突变引起的皮肤屏障异常与血清25-羟基维生素D浓度升高有关。 - Suppr

Skin barrier abnormality caused by filaggrin (FLG) mutations is associated with increased serum 25-hydroxyvitamin D concentrations.

作者信息

Thyssen Jacob P, Thuesen Betina, Huth Cornelia, Standl Marie, Carson Charlotte G, Heinrich Joachim, Krämer Ursula, Kratzsch Jürgen, Berg Nikolaj D, Menné Torkil, Johansen Jeanne D, Carlsen Berit C, Schwab Sigrid, Thorand Barbara, Munk Marianne, Wallaschofski Henri, Heickendorff Lene, Meldgaard Michael, Szecsi Pal B, Stender Steen, Bønnelykke Klaus, Weidinger Stephan, Bisgaard Hans, Linneberg Allan

出版信息

J Allergy Clin Immunol. 2012 Nov;130(5):1204-1207.e2. doi: 10.1016/j.jaci.2012.06.046. Epub 2012 Aug 24.

DOI:10.1016/j.jaci.2012.06.046

PMID:22921868

Abstract

摘要

相似文献

Skin barrier abnormality caused by filaggrin (FLG) mutations is associated with increased serum 25-hydroxyvitamin D concentrations.由丝聚合蛋白（FLG）突变引起的皮肤屏障异常与血清25-羟基维生素D浓度升高有关。

J Allergy Clin Immunol. 2012 Nov;130(5):1204-1207.e2. doi: 10.1016/j.jaci.2012.06.046. Epub 2012 Aug 24.

Filaggrin genotype and skin diseases independent of atopic dermatitis in childhood.丝聚合蛋白基因型与儿童期独立于特应性皮炎的皮肤疾病

Pediatr Allergy Immunol. 2016 Mar;27(2):162-8. doi: 10.1111/pai.12511. Epub 2015 Dec 21.

South African amaXhosa patients with atopic dermatitis have decreased levels of filaggrin breakdown products but no loss-of-function mutations in filaggrin.患有特应性皮炎的南非科萨族患者中，中间丝聚合蛋白降解产物水平降低，但中间丝聚合蛋白无功能丧失突变。

J Allergy Clin Immunol. 2014 Jan;133(1):280-2.e1-2. doi: 10.1016/j.jaci.2013.09.053.

Filaggrin loss-of-function mutations are not a predisposing factor for atopic dermatitis in an Ishigaki Island under subtropical climate.在亚热带气候下的石垣岛，丝聚合蛋白功能丧失突变并非特应性皮炎的诱发因素。

J Dermatol Sci. 2014 Oct;76(1):10-5. doi: 10.1016/j.jdermsci.2014.06.004. Epub 2014 Jul 2.

Hand eczema, atopic dermatitis and filaggrin mutations in adult Danes: a registry-based study assessing risk of disability pension.丹麦成年人手部湿疹、特应性皮炎和丝聚蛋白突变：基于登记的研究评估残疾抚恤金风险。

Contact Dermatitis. 2017 Aug;77(2):95-105. doi: 10.1111/cod.12786. Epub 2017 Apr 20.

Knockdown of filaggrin impairs diffusion barrier function and increases UV sensitivity in a human skin model.丝聚合蛋白缺失会损害皮肤扩散屏障功能，并增加人体皮肤模型对 UV 的敏感性。

J Invest Dermatol. 2010 Sep;130(9):2286-94. doi: 10.1038/jid.2010.115. Epub 2010 May 6.

Loss-of-function mutations in filaggrin gene and malignant melanoma: a case-control study.丝聚合蛋白基因突变与恶性黑素瘤：病例对照研究。

J Eur Acad Dermatol Venereol. 2018 Feb;32(2):242-244. doi: 10.1111/jdv.14532. Epub 2017 Sep 12.

It Remains Unknown Whether Filaggrin Gene Mutations Evolved to Increase Cutaneous Synthesis of Vitamin D.Filaggrin 基因突变是否是为了增加皮肤合成维生素 D 仍不得而知。

Genome Biol Evol. 2017 Apr 1;9(4):900-901. doi: 10.1093/gbe/evx049.

Carriers of filaggrin gene (FLG) mutations avoid professional exposure to irritants in adulthood.FLG 基因突变携带者在成年后避免职业性接触刺激物。

Contact Dermatitis. 2013 Dec;69(6):355-62. doi: 10.1111/cod.12097. Epub 2013 Jun 28.

IgE sensitization in relation to preschool eczema and filaggrin mutation.特应性致敏与学龄前特应性皮炎和丝聚蛋白突变的关系。

J Allergy Clin Immunol. 2017 Dec;140(6):1572-1579.e5. doi: 10.1016/j.jaci.2017.04.008. Epub 2017 Apr 26.

引用本文的文献

Ethnic and Racial Disparities in Clinical Manifestations of Atopic Dermatitis.特应性皮炎临床表现中的种族和民族差异。

Arch Intern Med Res. 2024;7(2):114-133. doi: 10.26502/aimr.0170. Epub 2024 Jun 4.

Vitamin D deficiency and atopic dermatitis severity in a Bangladeshi population living in East London: A cross-sectional study.居住在东伦敦的孟加拉人群体中维生素D缺乏与特应性皮炎严重程度：一项横断面研究。

Skin Health Dis. 2024 Mar 12;4(3):e358. doi: 10.1002/ski2.358. eCollection 2024 Jun.

Overview of Atopic Dermatitis in Different Ethnic Groups.不同种族中特应性皮炎概述

J Clin Med. 2023 Apr 4;12(7):2701. doi: 10.3390/jcm12072701.

Vitamin D, skin filaggrin, allergic sensitization, and race.维生素 D、皮肤丝聚蛋白、过敏致敏和种族。

Ann Allergy Asthma Immunol. 2022 Apr;128(4):399-407.e3. doi: 10.1016/j.anai.2022.01.017. Epub 2022 Jan 23.

Vitamin D Status in Distinct Types of Ichthyosis: Importance of Genetic Type and Severity of Scaling.不同类型鱼鳞病患者的维生素 D 状态：遗传类型和鳞屑严重程度的重要性。

Acta Derm Venereol. 2021 Sep 15;101(9):adv00546. doi: 10.2340/00015555-3887.

Causal Analysis Shows Evidence of Atopic Dermatitis Leading to an Increase in Vitamin D Levels.因果分析显示特应性皮炎导致维生素D水平升高的证据。

J Invest Dermatol. 2021 May;141(5):1339-1341. doi: 10.1016/j.jid.2020.09.013. Epub 2020 Oct 15.

Genetics in Atopic Dermatitis: Historical Perspective and Future Prospects.特应性皮炎的遗传学：历史透视与未来展望。

Acta Derm Venereol. 2020 Jun 9;100(12):adv00163. doi: 10.2340/00015555-3513.

Genome-wide association study identifies 143 loci associated with 25 hydroxyvitamin D concentration.全基因组关联研究鉴定出 143 个与 25 羟维生素 D 浓度相关的位点。

Nat Commun. 2020 Apr 2;11(1):1647. doi: 10.1038/s41467-020-15421-7.

It Remains Unknown Whether Filaggrin Gene Mutations Evolved to Increase Cutaneous Synthesis of Vitamin D.Filaggrin 基因突变是否是为了增加皮肤合成维生素 D 仍不得而知。

Genome Biol Evol. 2017 Apr 1;9(4):900-901. doi: 10.1093/gbe/evx049.

Vitamin D should be supplemented more actively in elderly patients with coronary heart disease combined with COPD.冠心病合并慢性阻塞性肺疾病的老年患者应更积极地补充维生素D。

Int J Chron Obstruct Pulmon Dis. 2016 Jun 21;11:1359-65. doi: 10.2147/COPD.S105671. eCollection 2016.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验

Skin barrier abnormality caused by filaggrin (FLG) mutations is associated with increased serum 25-hydroxyvitamin D concentrations.

作者信息

出版信息

相似文献

引用本文的文献

文献AI研究员

用中文搜PubMed

文档翻译

Suppr 超能文献

相似文献

引用本文的文献