Salameh Johnny S, Souayah Nizar, Chong Peter S T
Department of Neurology, University of Massachusetts Medical Center, Worcester, MA 01605, USA.
J Clin Neuromuscul Dis. 2012 Sep;14(1):40-4. doi: 10.1097/CND.0b013e3182596166.
Motor conduction block is one of the well-known neurophysiologic features of primary demyelinating polyneuropathy. In contrast, activity-dependent conduction block (motor conduction block after brief maximum voluntary contraction) is a "rare" neurophysiologic finding in primary demyelinating polyneuropathy. We are reporting the first known case of multifocal acquired demyelinating sensory and motor polyneuropathy with a well-documented activity-dependent conduction block of the ulnar nerve at the forearm segment that transformed into a typical motor response with abnormal temporal dispersion.
运动传导阻滞是原发性脱髓鞘性多发性神经病的著名神经生理学特征之一。相比之下，活动依赖性传导阻滞（短暂最大自主收缩后出现的运动传导阻滞）在原发性脱髓鞘性多发性神经病中是一种“罕见”的神经生理学表现。我们报告了首例有充分记录的多灶性获得性脱髓鞘性感觉和运动性多发性神经病病例，其在前臂段尺神经存在活动依赖性传导阻滞，随后转变为具有异常时间离散的典型运动反应。
