Postgraduate Studies Program in Cardiology, Universidade Federal do Rio, Grande do Sul, Brazil.
J Hypertens. 2012 Nov;30(11):2112-7. doi: 10.1097/HJH.0b013e3283588268.
To investigate the association between hypertension and musculoskeletal complaints among men and women selected by a population-based sample.
A cross-sectional study, with participants selected using a multistage sampling procedure and interviewed at home, was conducted to investigate the association between hypertension and musculoskeletal complaints. Hypertension was defined by the average of four measurements of blood pressure (BP) at least 140/90 mmHg or use of BP-lowering drugs. Musculoskeletal complaints in the 3 months before the interview were investigated by a structured questionnaire.
Among 1858 participants, 58% were women, 64% were 18-49 years old, and 45% had up to 8 years of education. The prevalence of musculoskeletal complaint was 33% [95% confidence interval (CI) 30-36] and of hypertension was 34% (95% CI 32-37). Men and women with hypertension had higher prevalence of musculoskeletal complaint, which was no longer significant in women after adjustment for age, educational level, skin color, BMI, physical inactivity, diabetes mellitus, alcohol consumption, smoking and history of cardiovascular disease. Hypertensive men with uncontrolled hypertension using BP agents had higher prevalence of musculoskeletal complaint (adjusted risk ratio = 1.78; 95% CI 1.11-2.86).
Chronic musculoskeletal complaints are more frequent in men with uncontrolled hypertension under drug treatment. The absence of association in women and in hypertensive men not taking BP drugs suggest that hypertension is not a risk or protection against musculoskeletal complaints.
调查人群抽样的男性和女性中高血压与肌肉骨骼投诉之间的关联。
采用多阶段抽样程序选择参与者，并在家中进行访谈，进行横断面研究，以调查高血压与肌肉骨骼投诉之间的关联。高血压通过至少 140/90 毫米汞柱的四次血压测量的平均值或使用降压药物来定义。在访谈前 3 个月，通过结构化问卷调查肌肉骨骼投诉。
在 1858 名参与者中，58%为女性，64%年龄在 18-49 岁之间，45%受教育程度不超过 8 年。肌肉骨骼投诉的患病率为 33%（95%可信区间为 30-36），高血压的患病率为 34%（95%可信区间为 32-37）。高血压男性和女性肌肉骨骼投诉的患病率较高，但在调整年龄、教育程度、肤色、BMI、身体活动不足、糖尿病、饮酒、吸烟和心血管疾病史后，女性的相关性不再显著。未服用降压药物的高血压男性中，血压控制不佳的高血压患者肌肉骨骼投诉的患病率更高（调整风险比=1.78；95%可信区间为 1.11-2.86）。
在接受药物治疗的未控制高血压男性中，慢性肌肉骨骼投诉更为常见。女性和未服用降压药物的高血压男性中不存在相关性，这表明高血压不是肌肉骨骼投诉的风险或保护因素。
