Sharma R C, Gautam A S
Malaria Research Centre (Field Station), Civil Hospital, Nadiad, India.
Indian J Malariol. 1990 Sep;27(3):157-62.
Irregular and inadequate surveillance of fever cases, misdiagnosis of positive cases and the near nonexistence of an appropriate monitoring mechanism culminated in an outbreak of malaria in a village of Kheda district, Gujarat. Plasmodium falciparum (Pf) resistance to chloroquine must have aided in the increase of Pf cases. DDT still appears to be effective against the vector, A. culicifacies in the area. Amodiaquine was successful in clearing asexual parasites in 83% cases which were resistant to chloroquine. Bioenvironmental control of malaria is suggested in order to delay the development of insecticidal resistance in vector mosquitoes.
对发热病例的监测不规范且不充分、对阳性病例的误诊以及几乎不存在适当的监测机制,最终导致古吉拉特邦凯达区一个村庄爆发疟疾。恶性疟原虫(Pf)对氯喹的耐药性肯定助长了Pf病例的增加。滴滴涕在该地区似乎仍对媒介库蚊有效。氨酚喹成功清除了83%对氯喹耐药病例中的无性寄生虫。建议对疟疾进行生物环境控制,以延缓媒介蚊虫产生抗药性。