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胰十二指肠切除术后胰瘘的挽救性胰胃吻合术

Salvage pancreaticogastrostomy for pancreatic fistulae after pancreaticoduodenectomy.

作者信息

Govil Sanjay

机构信息

Bangalore Institute of Oncology Specialty Centre, HCG Towers, #8 P. Kalinga Rao Road, Sampangiram Nagar, Bangalore, 560 027, India.

出版信息

Indian J Gastroenterol. 2012 Sep;31(5):263-6. doi: 10.1007/s12664-012-0213-1. Epub 2012 Aug 28.

Abstract

Pancreatic anastomotic dehiscence after pancreaticoduodenectomy (PD) remains a common problem. Although the management of this condition is mostly conservative, some patients require surgical intervention. This study reviews our experience with surgical intervention in this clinical setting. All patients who underwent PD by the author between 1999 and 2011 were reviewed. The causes for reoperation and mortality after PD were evaluated. The nature of the operative intervention and outcome in those who underwent reoperation for postoperative pancreatic fistula were analyzed. Reoperation was necessary in a total of 36/208 patients in this series and the overall mortality for the entire series was 6.25 % (13/208). Twelve of these 36 reoperations in 208 patients were for treatment of pancreatic anastomotic dehiscence after PD. Five (42 %) patients reoperated for anastomotic dehiscence died, including four of six patients that underwent surgical drainage of percutaneously inaccessible collections and one of two patients that underwent completion pancreatectomy. None of those who underwent salvage pancreaticogastrostomy (PG) died, nor did they require additional interventions prior to discharge from hospital. In our experience, salvage PG was an effective and organ function preserving technique to manage pancreatic anastomotic dehiscence after PD.

摘要

胰十二指肠切除术后(PD)的胰肠吻合口裂开仍然是一个常见问题。尽管这种情况的处理大多是保守的,但有些患者需要手术干预。本研究回顾了我们在这种临床情况下进行手术干预的经验。对1999年至2011年间由作者实施PD手术的所有患者进行了回顾。评估了PD术后再次手术的原因和死亡率。分析了因术后胰瘘而接受再次手术患者的手术干预性质和结果。本系列中共有36/208例患者需要再次手术,整个系列的总死亡率为6.25%(13/208)。这208例患者中的36例再次手术中有12例是为了治疗PD术后的胰肠吻合口裂开。因吻合口裂开而再次手术的5例(42%)患者死亡,其中包括6例对经皮无法到达的积液进行手术引流患者中的4例,以及2例接受全胰切除术患者中的1例。接受挽救性胰胃吻合术(PG)的患者无一死亡,在出院前也无需额外干预。根据我们的经验,挽救性PG是一种有效且能保留器官功能的技术,可用于处理PD术后的胰肠吻合口裂开。

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