Alkek Eye Center, Cullen Eye Institute, Baylor College of Medicine, Houston, TX 77030, USA.
Br J Ophthalmol. 2012 Nov;96(11):1395-8. doi: 10.1136/bjophthalmol-2011-301353. Epub 2012 Aug 24.
To describe the long-term outcomes of lens-sparing vitrectomy (LSV) for retinopathy of prematurity (ROP).
Single-centre retrospective case series of eyes that underwent LSV for ROP between 1998 and 2005 and had a follow-up of at least 5 years. The primary outcome was the mean visual acuity, and secondary outcomes were the proportion of eyes without functional vision, proportion of eyes with anatomic success, proportion of Stage 4A eyes with vision better than 20/400, proportion of Stage 4B eyes with vision better than 20/800.
Thirty-seven eyes of 30 patients (mean age at last follow-up: 7.1 years) were included in the study, while an additional 23 patients had been lost to follow-up and were not included in the study. Of eyes that underwent LSV for Stage 4A or 4B: 63% had measurable visual acuity (mean logMAR 0.92 for Stage 4A, 1.63 for Stage 4B), 19% had form vision, but neurological comorbidities precluded visual acuity measurement, and the remaining 18% had light perception or no light perception.
While most eyes that underwent LSV for Stage 4A or 4B ROP maintain useful vision with long-term follow-up, approximately one-fifth of eyes had no functional vision, and in a further fifth, vision could not be measured due to severe neurological impairment.
描述早产儿视网膜病变（ROP）晶状体保留玻璃体切除术（LSV）的长期结果。
对 1998 年至 2005 年间接受 LSV 治疗 ROP 并随访至少 5 年的单中心回顾性病例系列研究。主要结局是平均视力，次要结局是无功能视力眼的比例、解剖成功眼的比例、4A 期视力优于 20/400 的眼的比例、4B 期视力优于 20/800 的眼的比例。
30 例患者的 37 只眼（末次随访时的平均年龄为 7.1 岁）纳入研究，另有 23 例患者失访，未纳入研究。行 LSV 治疗的 4A 期或 4B 期眼：63%有可测量视力（4A 期平均 logMAR 0.92，4B 期 1.63），19%有形态视力，但神经合并症妨碍视力测量，其余 18%有光感或无光感。
虽然大多数接受 LSV 治疗的 4A 期或 4B 期 ROP 眼在长期随访中保持有用视力，但约五分之一的眼无功能视力，另有五分之一的眼因严重神经损伤而无法测量视力。
