CLV3 作为茎尖分生组织调节肽并不激活先天免疫。
The shoot apical meristem regulatory peptide CLV3 does not activate innate immunity.
机构信息
The Sainsbury Laboratory, Norwich Research Park, Norwich NR4 7UH, United Kingdom.
出版信息
Plant Cell. 2012 Aug;24(8):3186-92. doi: 10.1105/tpc.111.091264. Epub 2012 Aug 24.
Abstract
The Arabidopsis thaliana leucine-rich repeat receptor kinase FLAGELLIN SENSING2 (FLS2) is required for the recognition of bacterial flagellin in innate immunity. Recently, FLS2 was proposed to act as a multispecific receptor recognizing unrelated exogenous and endogenous peptide ligands, including CLAVATA3 (CLV3), a key regulator of shoot meristem stem cell production. Here, we report experimental evidence demonstrating that FLS2 does not recognize CLV3 and that the shoot apical meristem is immune to bacteria independently of CLV3 perception.
摘要
拟南芥富含亮氨酸重复受体激酶 FLAGELLIN 感应 2（FLS2）是先天免疫中识别细菌鞭毛蛋白所必需的。最近，FLS2 被提出作为一种多特异性受体，识别不相关的外源性和内源性肽配体，包括 CLAVATA3（CLV3），这是芽分生组织干细胞产生的关键调节剂。在这里，我们报告了实验证据，证明 FLS2 不识别 CLV3，并且芽尖分生组织对细菌具有免疫性，而不依赖于 CLV3 的感知。
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