海星卵胶膜中诱导顶体反应物质的结构：一个小型综述。

Structure of acrosome reaction-inducing substance in the jelly coat of starfish eggs: a mini review.

机构信息

The Open University of Japan, Chiba, Japan.

出版信息

Biochem Biophys Res Commun. 2012 Aug 31;425(3):595-8. doi: 10.1016/j.bbrc.2012.08.033.

DOI:10.1016/j.bbrc.2012.08.033

Abstract

Our knowledge at present on the structure of acrosome-reaction inducing substance (ARIS) in the jelly coat of starfish eggs is summarized. ARIS ia a proteoglycan-like molecule consisting of very long, linear, and highly sulfated glycans and three ARIS proteins, ARIS1-3. Detailed structures of the major glycan of ARIS and of ARIS1-3 are discussed. 3D-models of ARIS glycans are also presented. Phylogenetic distribution of ARIS proteins and/or genes indicates that ARIS genes are well preserved from the Ctenophore to Cephalochordata. In the Echinodermata, ARIS1-3 and ARIS genes were detected in all classes except for sea urchins.

摘要

目前，我们对海星卵胶膜中顶体反应诱导物质（ARIS）的结构的了解进行了总结。ARIS 是一种类似蛋白聚糖的分子，由非常长的、线性的和高度硫酸化的聚糖和三种 ARIS 蛋白（ARIS1-3）组成。讨论了 ARIS 的主要聚糖和 ARIS1-3 的详细结构。还呈现了 ARIS 聚糖的 3D 模型。ARIS 蛋白和/或基因的系统发生分布表明，从栉水母到头索动物，ARIS 基因都得到了很好的保存。在棘皮动物中，除了海胆外，所有类群中都检测到了 ARIS1-3 和 ARIS 基因。