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一名活动性肺结核患者新发糖尿病。

New onset diabetes in a patient with active tuberculosis.

作者信息

Skowroński Marcin, Halicka Anna, Barinow-Wojewódzki Aleksander

机构信息

Wielkopolskie Centrum Pulmonologii i Torakochirurgii, Ludwikowo k/Poznania, 62–050 Mosina, Polska.

出版信息

Pneumonol Alergol Pol. 2012;80(5):467-70.

PMID:22926909
Abstract

The present report describes the coincidence of pulmonary tuberculosis (TB) and metabolic disorder such as diabetes. A patient's bronchoalveolar lavage was found to be positive for acid-fast bacilli (AFB) with following growth of Mycobacterium tuberculosis and complete sensitivity to first line anti-TB drugs. At the same time, the patient presented with typical diabetes manifestation and subsequently required insulin therapy. Combined treatment resulted in significant clinical improvement and gradual resolution of both TB and diabetes symptoms. Therefore, we would like to highlight the value of appropriate medical management of these disorders sharing at least some clinical symptoms and signs such as weight loss and fatigue. Moreover, a growing body of evidence indicates that diabetes may play a role as a risk factor for TB. Consequently, the increasing diabetes prevalence may be a danger to TB control.

摘要

本报告描述了肺结核(TB)与代谢紊乱如糖尿病同时存在的情况。一名患者的支气管肺泡灌洗发现抗酸杆菌(AFB)呈阳性,随后结核分枝杆菌生长,且对一线抗结核药物完全敏感。与此同时,该患者出现典型的糖尿病表现,随后需要胰岛素治疗。联合治疗使临床症状显著改善,结核病和糖尿病症状逐渐缓解。因此,我们想强调对这些至少有一些共同临床症状和体征(如体重减轻和疲劳)的疾病进行适当医疗管理的价值。此外,越来越多的证据表明,糖尿病可能是结核病的一个危险因素。因此,糖尿病患病率的上升可能对结核病控制构成威胁。

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引用本文的文献

1
Tuberculosis and diabetes mellitus - an underappreciated association.结核病和糖尿病——被低估的关联。
Arch Med Sci. 2014 Oct 27;10(5):1019-27. doi: 10.5114/aoms.2014.46220. Epub 2014 Oct 23.