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实性假乳头状癌:病例研究与文献综述

Solid-pseudopapillary carcinoma: a case study and literature review.

作者信息

Mat Zin Anani Aila, Shakir K A R, Aminuddin A R, Mahedzan M R, Irnawati W A R, Andee D Z, Hassan S A, Ezane M A, Hasnan M N

机构信息

Department of Pathology, School of Medical Sciences, Universiti Sains Malaysia, Kelantan, Malaysia.

出版信息

BMJ Case Rep. 2012 Aug 27;2012:bcr2012006495. doi: 10.1136/bcr-2012-006495.

Abstract

Solid-pseudopapillary tumour (SPT) is a rare exocrine tumour of the pancreas and is considered to have low malignant potential. Few morphological criteria are used to predict malignant behaviour such as equivocal perineural invasion, angioinvasion and invasion to surrounding tissue, and should be designated as solid-pseudopapillary carcinoma (SPC). We report a case of SPC. Clinical and radiological findings are typical for SPT with no metastatic disease. There is no tumour recurrence after 4 months postresection. Clinical history and radiological findings were retrieved from the patient's record sheet and Viarad system. H&E staining and few immunoproxidase staining were reviewed by several pathologists. The histological findings are typical for SPT, with additional perineural invasion. There is no angioinvasion or capsular invasion identified. This is our first experience in diagnosing and managing SPC. We look forward to seeing the patient's disease status during her next routine follow-up. We expect good disease-free survival and very low risk of tumour recurrence, in view of only one risk factor (perineural invasion) and uninvolved surgical margins by the tumour.

摘要

实性假乳头状肿瘤(SPT)是一种罕见的胰腺外分泌肿瘤,被认为具有低恶性潜能。很少有形态学标准用于预测恶性行为,如可疑的神经周围侵犯、血管侵犯和对周围组织的侵犯,符合这些情况的应被诊断为实性假乳头状癌(SPC)。我们报告一例SPC病例。临床和影像学表现为典型的SPT,无转移病灶。切除术后4个月无肿瘤复发。临床病史和影像学表现从患者病历和Viarad系统中获取。几位病理学家对苏木精-伊红染色和少量免疫过氧化物酶染色进行了复查。组织学表现为典型的SPT,伴有额外的神经周围侵犯。未发现血管侵犯或包膜侵犯。这是我们诊断和处理SPC的首例经验。我们期待在患者下次常规随访时了解其疾病状况。鉴于仅有一个风险因素(神经周围侵犯)且肿瘤切缘未受累,我们预计患者无病生存期良好且肿瘤复发风险极低。

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本文引用的文献

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Clinical experiences of solid pseudopapillary tumors of the pancreas in China.中国胰腺实性假乳头状瘤的临床经验
J Gastroenterol Hepatol. 2008 Dec;23(12):1847-51. doi: 10.1111/j.1440-1746.2008.05526.x. Epub 2008 Aug 24.
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Surgical outcome of solid pseudopapillary tumor of the pancreas.胰腺实性假乳头状瘤的手术结果
J Hepatobiliary Pancreat Surg. 2008;15(3):318-21. doi: 10.1007/s00534-007-1264-z. Epub 2008 Jun 6.

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