Isfahan, Iran From the Department of Plastic and Reconstructive Surgery and Medical Education Research Center, Isfahan University of Medical Sciences.
Plast Reconstr Surg. 2012 Sep;130(3):571-578. doi: 10.1097/PRS.0b013e31825dc00e.
The eyebrow and eyelash are two major sites in facial hair transplantation. Different methods have been experienced for better results. Surgeons tend to use smaller grafts. The authors modified the follicular isolation technique and added de-epithelialization to reduce complications and improve outcomes.
Sixty patients were allocated to either the isolation group or the isolation plus de-epithelialization group. Some patients underwent both eyebrow and eyelash transplantation; therefore, 79 procedures were performed on 60 patients. Scar formation, number and percentage of surviving transplanted hairs, hair growth orientation, and satisfaction with outcome were reviewed at 6 months.
The mean number of preserved transplanted hairs in eyebrow transplantation at follow-up was not significantly different between the two groups, but the mean percentage of preserved transplanted hairs was significantly higher in the isolation plus de-epithelialization group. In eyelash reconstruction, the mean number and percentage of surviving hairs were significantly higher in the isolation + de-epithelialization group than in the isolation-only group. The isolation + de-epithelialization group had more cases of normal hair growth direction in both eyebrow and eyelash transplantation cases, although the difference was statistically significant only in eyebrow reconstruction.
This study showed that follicular isolation plus de-epithelialization had better outcomes and fewer complications than did follicular isolation alone. This could be due to less need for suture in recipient sites, less risk for burying of epithelium of graft in the recipient site, less need for manipulation, lower graft volume, and less need for blood for survival and for removal of sweat glands.
CLINICAL QUESTION/LEVEL OF EVIDENCE: : Therapeutic, II.
眉毛和睫毛是面部毛发移植的两个主要部位。为了达到更好的效果，人们尝试了不同的方法。外科医生倾向于使用更小的移植体。作者对毛囊分离技术进行了改良，并增加了去上皮化处理，以减少并发症，改善效果。
60 名患者被分配到分离组或分离加去上皮化组。一些患者同时接受了眉毛和睫毛移植，因此，共有 60 名患者进行了 79 例手术。在 6 个月时，评估了瘢痕形成、移植存活毛发的数量和百分比、毛发生长方向以及对结果的满意度。
在随访时，眉毛移植中保留的移植毛发数量在两组之间无显著差异，但分离加去上皮化组中保留的移植毛发百分比显著更高。在睫毛重建中，分离加去上皮化组中存活的毛发数量和百分比均显著高于分离组。分离加去上皮化组在眉毛和睫毛移植中，正常毛发生长方向的病例更多，但仅在眉毛重建中差异具有统计学意义。
本研究表明，与单纯毛囊分离相比，毛囊分离加去上皮化具有更好的效果和更少的并发症。这可能是由于在受区缝合的需求减少、移植体上皮埋入受区的风险降低、操作的需求减少、移植体体积减小、以及用于存活和去除汗腺的血液需求减少。
临床问题/证据水平：治疗，II 级。
