Berg Peter, Lindhardt Bjarne Ørskov
Lunge- og Infektionsmedicinsk Afdeling, Hillerød Hospital, Dyrehavevej 29, 3400 Hillerød, Denmark.
Ugeskr Laeger. 2012 Aug 27;174(35):1986-9.
Reduction of antimicrobial resistance in microorganisms is imperative. Pneumonia is important in this matter because of its high incidence, subjective diagnostic criteria, and variations in aetiology. Research has focused on the use of a procalcitonin-guided algorithm for antimicrobial stewardship with promising reductions in antibiotic use and treatment duration, but more research is needed in order to draw a final conclusion. Lack of objective diagnostic criteria, methodological challenges in research, a future focus on primary care, and the need for a cost-benefit analysis should be considered.
降低微生物的抗药性势在必行。肺炎在这方面很重要，因为其发病率高、诊断标准主观且病因各异。研究集中在使用降钙素原指导的抗菌管理算法，有望减少抗生素使用和治疗时长，但还需要更多研究才能得出最终结论。应考虑缺乏客观诊断标准、研究中的方法学挑战、未来对初级保健的关注以及成本效益分析的必要性。
