Maack Kim Hovgaard, Tarp Britta
Hjertemedicinsk Afdeling B, Aarhus Universitetshospital, Skejby, Brendstrupgårdsvej 100, 8200 Aarhus N, Denmark.
Ugeskr Laeger. 2012 Aug 27;174(35):1997-8.
The incidence of nosocomial fungal infections has increased over the past 20 years. Candida albicans is the most commonly involved pathogen. Concurrently, the number of non-albicans species with decreased susceptibility to commonly used antifungal agents has increased significantly. Invasive candidiasis is associated with significant morbidity and mortality. We present a case of unusually massive infection with a number of different Candida species, which caused severe prolonged infection in a critically ill patient.
在过去20年中,医院获得性真菌感染的发生率有所上升。白色念珠菌是最常涉及的病原体。与此同时,对常用抗真菌药物敏感性降低的非白色念珠菌种类数量显著增加。侵袭性念珠菌病与显著的发病率和死亡率相关。我们报告一例由多种不同念珠菌引起的异常大量感染病例,该感染在一名重症患者中导致了严重的长期感染。