Programa de Pós-Graduação em Medicina Tropical, Fundação de Medicina Tropical Dr. Heitor Vieira Dourado, Universidade do Estado do Amazonas, Manaus, AM, Brasil.
Rev Soc Bras Med Trop. 2012 Jul-Aug;45(4):530-2. doi: 10.1590/s0037-86822012000400024.
The occurrence of tuberculosis with first-line multidrug resistance leads to the use of alternative medications, often at higher costs, longer treatment periods, and greater clinical complexity. Here, we report 3 patients with multidrug-resistant tuberculosis. One patient with human immunodeficiency virus died before the sensitivity test was performed. The early diagnosis of multidrug-resistant tuberculosis and appropriate treatment should be priorities of the National Tuberculosis Control Program in order to break the chain of transmission. In addition, the possibility of substituting the proportion method with more modern and faster techniques should be urgently evaluated.
耐一线药物的结核病的发生导致了替代药物的使用，这些药物往往费用更高，治疗周期更长，临床复杂性更大。在这里，我们报告了 3 例耐多药结核病患者。1 例艾滋病毒感染者在进行药敏试验前死亡。及早诊断耐多药结核病并进行适当治疗应成为国家结核病控制规划的重点，以打破传播链。此外，应紧急评估用更现代和更快的技术替代比例法的可能性。
